For clinical research

Objective intake data for your study

DoryGo records each dose as it is taken — passively, at compartment level and for the full regimen. Your analysis works with measured intake instead of diaries, pill counts or refill records.

Sensor pill box on a kitchen table
Fig. 1 — Sensor pill box at home
Passive
No patient input. Every compartment opening is recorded by the box.
Export
Timestamped intake events as analysis-ready CSV or REDCap import.
Swiss
Built in Zurich, hosted in Switzerland, GDPR-aligned.

Not running a study?
Same product, different entry point.

01 — The problem

Adherence is measured with the methods least able to capture it

Adherence is a variable in almost every study involving oral medication. In most protocols it is still assessed through diaries, returned-pill counts or refill records — methods that show whether medication was available, not whether and when it was taken.

01

Diaries and pill counts are indirect

Both depend on what participants record or bring back. Neither shows when a dose was taken.

02

Single-container monitors stop at one drug

Electronic caps record openings of one container. With several medications, each needs its own device, or some go unmeasured.

03

Intake and effect are confounded

Without measured intake, a weak treatment effect cannot be told apart from a treatment that was not taken as specified.

25–30%

of plasma samples contained the study drug, while self-report and returned pill counts indicated 86–90% adherence (HIV prevention trial, women in South Africa, Uganda and Zimbabwe).

Source: Marrazzo et al., New England Journal of Medicine, 2015 (VOICE trial)

02 — For your study

Intake as a measured variable, not an assumption

Dose-level

Each compartment opening is recorded as a timestamped event.

Full regimen

One blister holds all oral medication of a participant, so one device covers the regimen.

Low burden

No diary, no app confirmation. Participants take their medication; the box records it.

Measured intake changes what a study can say. It separates the effect of a treatment from the extent to which it was taken, supports per-protocol analyses on recorded rather than assumed intake, and allows timing — not only the number of doses — to enter the analysis.

We provide the measurement and its documentation; the analysis stays with your team. The measurement principle and its limitations are described so that they can be stated in a methods section.

03 — The product

Three parts, one continuous record

Part 01

Pre-sorted multi-dose blister

A pharmacy sorts the full regimen into dated, time-labelled compartments, so the patient never assembles a dose themselves.

  • —One compartment per intake time, printed with date and patient name
  • —Regimen changes handled at the pharmacy, not by the patient
  • —Removes the manual weekly re-sorting step entirely
Multi-dose blister tray with a printed patient label and four time-labelled compartments (night, evening, noon, morning); three are foil-sealed and the morning compartment is open with tablets
Fig. 2 — Multi-dose blister, 1 day × 4 slots
Part 02

Sensor pill box

A new blister is inserted each day. The box registers each compartment opening passively — no app step, no confirmation, nothing else for the patient to remember.

  • —Timestamped event per opening, at compartment level
  • —Local buffering; syncs when a connection is available
  • —Works for patients who do not use a smartphone
Sensor pill box with lid open and blister compartments
Fig. 3 — Sensor pill box
Part 03

Patient app and dashboard

Patients see their own schedule and history. Your team sees recorded intake across all participating patients, sorted by missed and late doses.

  • —Overview of all participating patients, sorted by missed and late doses
  • —Intake history per patient
  • —Role-based access; export via FHIR or CSV
Patient app on a phone beside the team dashboard on a tablet
Fig. 4 — Patient app and dashboard

04 — Workflow

From the pharmacy bench to your team, in five steps

Step 1
Pharmacy sorts
The regimen is blistered by dose and time.
Step 2
Patient inserts blister
One action per day. Nothing else to operate.
Step 3
Box records each opening
Timestamp and compartment, recorded passively.
Step 4
Encrypted transfer
End-to-end encrypted, to Swiss-hosted storage.
Step 5
Study team receives the data
Timestamped events, ready for analysis.

05 — How step 1 is set up

Blistering runs through a licensed pharmacy partner in your market

There is one route, and it is deliberate. The pre-sorting is carried out by a local, licensed pharmacy partner, which we identify and set up together with your organisation. Dispensing stays where it is already regulated and already trusted. We equip that pharmacy with the sealing machine, the blisters and the foils, and we supply the box, the app, the dashboard and the integration.

National rules for dispensing, repackaging and medical-device classification differ, and they determine what is possible in your market. We clarify this per country before a pilot is scoped, and say so plainly where something is not viable.

Sealing machine on a pharmacy counter
Fig. 5 — Sealing machine for the pharmacy

06 — Evidence

What is shown, and what is not

Both columns are part of the same answer, and they carry the same weight. We would rather you take the right-hand column into your evaluation than discover it later.

What we can show today

  • The box records each compartment opening without any patient input, which removes self-report bias by construction.
  • The full chain is built and working end to end: blister, sensor box, patient app, dashboard.
  • In our own development testing, compartment openings were detected without error over several months of continuous bench testing, and battery life reached 18 months at four openings per day. These are internal measurements; independent validation is planned.

What we have not shown yet

  • Any effect on treatment results. Whether a reliable record of intake improves them is the question our pilots are designed to answer.
  • A validated cost-offset figure for a specific insured population. We will not quote an ROI we cannot defend.
  • Long-run persistence: how intake behaves after two years of use.
  • Deployment at the scale of a full health system.

07 — Pilot

What a study deployment looks like

Cohort
Study participants on oral medication, as defined in your protocol.
Duration
As specified in your protocol, plus a set-up and onboarding phase beforehand.
What we measure
Intake per dose and compartment, timing of each dose, data completeness and participant retention.
What we provide
Boxes, blister supply via a licensed pharmacy partner, participant onboarding material, data export, and a named contact in Zurich.
What we need from you
A principal investigator, ethics approval, a data-management contact, and the dosing schedule per participant.
What you get
An analysis-ready intake dataset you own, and a description of the measurement method for your publication.

08 — Integration

Into the systems you already run

FHIR
Intake events as standard resources, pulled or pushed.
Scientific data export
Analysis-ready extracts for research and evaluation teams.
REDCap
Intake events imported into your project as structured records.

09 — Compliance

Where the data sits, and who may see it

Swiss hosting
GDPR and Swiss FADP
Role-based access
Pseudonymisation
End-to-end encryption from box to dashboard

10 — About us

Who you would be working with

DoryHealth is a small Swiss company based in Zurich. We build and operate DoryGo ourselves, which means a pilot is run by the people who built the product rather than handed to an implementation team.

11 — Contact

Request a scoping call

Thirty minutes, no slide deck. We ask about your protocol and your data management, and tell you whether DoryGo fits your study.

DoryHealth AG · Hagenholzstrasse 81a, 8050 Zürich
hello@doryhealth.com

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